Short description

Price

719 EUR

Size

100ul

Catalog no.:

GEN601288

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Full description

Description

Sodium azide NaN3 is often used to prevent antibody degradation in 0,02% W/V concentrations. MBS Monoclonals supplies azide free antibodies on request.Recently MBS Monoclonals made this c-erbB2, phosphospeci?c (HER-2, neu Receptor) (BSA ) available without azide. It will stick less and is more suitable for ELISA or in vivo studies. However you need to store the @VV@ frozen and ship on dry ice.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Specificity and cross-reactivity

Highly specific to human activated, tyrosine-phosphorylated (pTyr1248) form of c-erbB-2. Does not crossreact with closely related receptors such as EGFR, HER-3 or HER-4. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Storage and shipping

Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Species reactivity

Human (Homo sapiens), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Other names

Chain P, Single Chain Fv Of C219 Heavy Chain V101l Mutant In Complex With Synthetic Epitope Peptide; N/A

Form/Appearance

Supplied as a liquid in PBS, pH 7.4. Also available with BSA and azide. See C0026-14.

Tested applications:

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification method

Affinity Purified by Protein G affinity chromatography.

Also known as

c-erbB2, phosphospeci?c

Subcategory

Mnoclonal antibodies

Source organism

Human (Homo sapiens)

Host organism

Mouse (Mus musculus)

Clonality

Monoclonal

Category

Antibodies

Clone

3F38

Immunoglobulin isotype

IgG1

Other gene names

N/A

Gene name synonims

N/A

Gene name

N/A

Concentration

N/A